Three days from 7th – 9th October, 2019 took place Asian Society of Veterinary Pathology conference 9th at Vietnam National University of Agricultrue with title ” New era of animal health: Zoonotic, foodborne, Emerging and oncologic diseases” In this conference had attended researchs from Thailan, Canada, South Korea, Philippine, Japan, India…and Vietnam. The speakers presented about new diseases especially African swine fever... In this column, we will introduce abbtracts of some research that it were published in the summary record of a conference
AFRICAN SWINE FEVER: CLINICAL AND PATHOLOGICAL FEATURES OF FILELD CASES IN VIETNAM
Bui Thi To Nga, Nguyen Thi Lan, Bui Tran Anh Dao, Nguyen Vu Son, Matoko Osaki, Kenji Kawashima, Kohtaro Miyazawa, Le Tran Phan
African swine fever (ASF) is a serious viral disease that has caused great economic losses to the pig industry. The ASF was detected in January 2019 in northern Vietnam and spread nationwide with rapidly.
To get insights about the clinical signs, gross and histopathological findings in the field cases of ASF in Vietnam.
Material and methods
486 pigs from 9 farms were subjected. Blood samples were collected and tested by real-time PCR. Clinical, gross and microscopic findings were evaluated, and immunohistochemistry was applied to detectthe ASF viral antigens in the parafin-embedded tissuses.
Infected pigs develop a high fever of up to 420C, hemorrhages especially extremities and ventral body. Abortion occurs in pregnant sows. Vomiting, hemorrhagic discharge from the nasal/anus, etaxial ans dispnea were frequently observed. Grossly, the dead pigs showed systemic hemorrhage.The spleen was enlarged with red dark color and friable. The hematoma-like visceral lymph nodes (LN) were frequently observed. The kidney and urinary bladder were petecchiae on cortical surface and ranal pelvis. Histopathologically, massive necrosis with prominent karyorrhexis was observed in lymph nodes, tonsil and spleen. The spleen lesion were diffuse degeneration and hemorrhagic necrosis in red and white pulps. The lung and kidney had congestion, thrombosis and infiltrale of monocuclear cells. In the liver, Kupffer’s cells degeneration and focal necrosis of hepatocytes can be seen. Immunohistochemicaly, ASF viral antigens were detectedin spleen, lung, kidney and LN. The strongest reactivity ứa obtained in LN and spleen.
The clinical, macroscopic and histopathological findings were consistent with the lesions described in the literature for peracute to acute form of ASF. Contact or consumption of carcass of pigs will be a big risk for introducing or speading diseaae because of high amounts of virus in blood and tissuses of affected pigs.